Dr. Adi Cohen is conducting a research study for women with pregnancy and lactation associated osteoporosis (PLO).
This study aims to define the bone defect that leads to PLO and to better understand the causes, risk factors, predictors of disease severity, and natural history of PLO so that we can develop targeted treatment approaches. This study has been approved by the Columbia University Irving Medical Center IRB: #AAAR0960.
You may qualify for this research if:
You have had low trauma or spontaneous fracture(s) during or shortly after pregnancy or breastfeeding.
Different participants may qualify for different aspects of the research study, including:
Online survey study
Genetic evaluation
Bone characterization studies that take place at Columbia University Medical Center
FOR MORE INFORMATION OR TO FIND OUT IF YOU MAY QUALIFY FOR DIFFERENT ASPECTS OF THIS RESEARCH STUDY
CALL: Mariana Bucovsky (Research Manager) or Dr. Adi Cohen at 212 305-7225
Click here for additional information and to download the study flyer.
Pregnancy and lactation associated osteoporosis (PLO) is a very rare early presentation of osteoporosis in which young women sustain fractures during, or soon after, pregnancy or breast-feeding (lactation).
Temporary decreases in bone density are a normal part of pregnancy and lactation—but fractures during this time are extremely rare. Fractures of the spine associated with severe back pain are most commonly described, but PLO can also be associated with hip fractures or other types of fracture.
In the most common scenario, PLO is discovered after a pregnant or breastfeeding woman develops severe back pain, and imaging reveals multiple vertebral fractures.
Some women with PLO have a pre-pregnancy diagnosis of osteoporosis, but most women with PLO have not been previously diagnosed with osteoporosis, and never had a bone assessment prior to the onset of symptoms.
The topic of PLO, as well as research being conducted, was discussed in this Columbia News article.